منابع مشابه
On bone-forming cells and blood vessels in bone development.
Replacement of nonvascular cartilage by bone and bone marrow is a critical step in bone development. In a recent issue of Developmental Cell, Maes et al. (2010) report that a distinct population of immature precursors of bone-forming cells migrate into the cartilage in intimate association with invading blood vessels.
متن کاملThe Behaviour of Blood Vessels after Experimental Transplantation of Bone.
Everybody with experience in bone transplantation agrees that autogenous grafts give the best results. In clinical practice, however, it is often difficult or impossible to get an autogenous graft. This is why bone banks exist. At the orthopaedic department of the University of Amsterdam we prefer the deep-frozen homogenous graft, but many surgeons use other types of banked bone. The results ob...
متن کاملFunctional tissue-engineered blood vessels from bone marrow progenitor cells.
OBJECTIVE Stem cells have significant potential for development of cell-based therapeutics for cardiovascular tissue regeneration. METHODS We developed a novel method for isolating smooth muscle cells (SMC) from ovine bone marrow using a tissue-specific promoter and fluorescence-activated cell sorting. RESULTS As compared to vascular SMC, bone marrow-derived smooth muscle progenitor cells (...
متن کاملBone Marrow Blood Vessels: Normal and Neoplastic Niche
Blood vessels are among the most important factors in the transport of materials such as nutrients and oxygen. This study will review the role of blood vessels in normal bone marrow hematopoiesis as well as pathological conditions like leukemia and metastasis. Relevant literature was identified by a Pubmed search (1992-2016) of English-language papers using the terms bone marrow, leukemia, meta...
متن کاملSonic Hedgehog-activated engineered blood vessels enhance bone tissue formation.
Large bone defects naturally regenerate via a highly vascularized tissue which progressively remodels into cartilage and bone. Current approaches in bone tissue engineering are restricted by delayed vascularization and fail to recapitulate this stepwise differentiation toward bone tissue. Here, we use the morphogen Sonic Hedgehog (Shh) to induce the in vitro organization of an endothelial capil...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2011
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.10.3.14519